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Appropriate scientific studies carried out to date have not demonstrated pediatric-particular troubles that could Restrict the usefulness of divalproex sodium in children. Nevertheless, security and efficacy have not been proven for other indications in small children, and to deal with seizures in young children more youthful than 10 years of age.T

If the entire each day dose exceeds 250 mg, it ought to be supplied in divided doses. In a very review of adjunctive therapy for elaborate partial seizures in which clients had been acquiring both carbamazepine or phenytoin As well as valproate, no adjustment of carbamazepine or phenytoin dosage was essential [see Scientific Scientific studies (14.